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Brain Science, Clozapine and Early Intervention in Psychosis

Dr. Deepak Sarpal is Assistant Professor of Psychiatry/Medical Director of Services for Treatment of Early Psychosis at WPH. This Podcast focuses upon Clozapine, a very valuable but underused treatment for refractory schizophrenia, also brain science involving functional imaging associated with patient improvement on anti-psychotic drugs. Findings include brain pre-frontal cortex connectivity and synchronization of function with brain striatum, limbic system structures, Globus Pallidus.

Released: 2/10/21

References

Tarcijonas, G, Sarpal, DK, Neuroimaging markers of antipsychotic treatment response in Schizophrenia: An overview of magnetic resonance imaging studies. Neurobiology of Disease 131 (2019)

Tarcijonas, G, Foran, W, Haas, GL, Luna, B, Sarpal, DK. Intrinsic Connectivity of the Globus Pallidus: An Uncharted Marker of Functional Prognosis in People with First-Episode Schizophrenia, Schizophrenia Bulletin 46 (2020) pgs. 184-192

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